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in Cell Metabolism , increased NAD⁺ availability stimulates PGC-1α through SIRT1 activation, leading to enhanced mitochondrial function and improved metabolic flexibility (Cantó et al., Cell Metabolism )

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To ensure sufficient intake of vitamin B12, older individuals are recommended to obtain it from supplements or fortified foods, such as ready-to-eat breakfast cereals

Dogs and cats can be deficient in this vitamin