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EC Opinion on the Murine Local Lymph Node Assay (LLNA) adopted by the SCCNFP during the 12th plenary meeting of 3 May 2000

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However, observed barrier defects and associated diarrhea even in these mice did not result in changes in claudin-1, -2, -3, and -4 expression and cellular distributions, but rather correlated with the rearrangement of cellular distribution of occludin, and to some extent with JAM proteins