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Furthermore, levels of Igs (IgG, IgG1, IgG2, IgG3, IgG4, IgA, IgM) and frequencies of lymphocytes (T cells: CD3 + , CD3 + CD4 + , CD3 + CD8 + , B cells: CD19 + , total memory CD19 + CD27 + , memory IgD + CD27 + , switched memory IgD - CD27 + , plasma cells IgM - CD38 ++ , naive IgM + /IgD + , CD21 low CD38 low , NK cells: CD16 + /CD56 + ) were recorded