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Using metabolic labeling with [ 32 P] and different mutants at the C terminal tail, the group of Law demonstrated that rat MOR (rMOR) displays a basal phosphorylation at S363 and T370 and DAMGO increases phosphorylation at T370 and S375 (El Kouhen et al., 2013) but failed to phosphorylate T370 (Doll et al., 2013)