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GSNO has been shown to decrease embolism from symptomatic carotid plaques and after carotid endarterectomy [135], carotid angioplasty [131], and vein graft [136] by limiting platelet activation

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Concurrently, activation of the Nrf2–GSH axis enhances the cellular antioxidant capacity, enabling tumor cells to maintain redox homeostasis under targeted therapy–induced oxidative stress, thus facilitating metabolic escape [77]