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Reported rodent-model adverse events are minimal at experimental doses, but "no toxicity noted in mice" is not equivalent to "safe in humans," especially for a compound affecting epigenetic regulators

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Dimethyl sulfoxide combined with intravesical cocktail therapy can lead to better outcomes after treatment, more effective reduction of inflammation, and higher quality of life for patients with interstitial cystitis.7 Other therapies for interstitial cystitis include injecting or infusing hyaluronic acid, botulinum toxin A, triamcinolone, resiniferatoxin, and platelet-rich plasma